Inhaled steroids are frequently indicated to treat individuals with early asthma complications.
According to certain recent researches, one can increase the standard quantity of inhaled steroids by 8 times, but benefits will be not enhanced in such situation. Ejaz Yousef, a specialist who has been involved in these studies, notes that if a physician observes that medical position of a person worsens, he/she can prescribe using oral steroids instead of enhancing the quantity of inhaled steroids. Enhancing the measure of inhaled corticosteroids is not without any side response. This factor causes various negative effects. For example, the hypothalamic-pituitary adrenal axis can be suppressed in such case.
Intake of inhaled corticosteroids was considered to be alternative to administering oral drugs. It was in 1997. It was advised to indicate inhaled corticosteroids as alternatives of oral drugs which are utilizable for individuals with asthma complications.
Later, certain studies have displayed that usage of enhanced dosages of inhaled steroids systematically doesn’t increase positive effects.
Yousef and his colleagues have conducted a study that involved almost 200 kids of 2-17 years. These kids were given inhaled corticosteroids during 3 months. They were chosen randomly for treatment for a period of 12 days. Any kid that had asthma complications was given inhaled steroids. Then the results were evaluated by the specialists.
No any kid who smoked, had symptoms of chronic asthma or lung pathology was involved in the study.
Patients had to let know about their negative reactions via telephone within 72 hours. So, it was reported about cough during nighttime, wheeze, shortness of breath and intolerance for exercises. Every result was evaluated according to a score which was ranged from 0 to 4. 0 meant no any effect; 4 meant the most enhanced severity level.
Only four children out of 82 the kids that were given enhanced measures of inhaled steroids had to apply systemic corticosteroids. 2 of them were given doubled dosages; others 2 were applying the dosage that was higher by 8 times than a usual one.
According to the results of the research, usefulness of the products, placebo effect, supervision of health care providers and treatment of patients during early stages of asthma exacerbation were responsible for getting positive results.
This as well as other studies manifest that not every story about steroids is linked with abuse and intake of them for performance-enhancing effects. Steroids are utilizable for many medical purposes.
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